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Ranked: U.S. States with Highest Chlamydia Cases

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Key Takeaways

Looking at chlamydia cases across U.S. states:

  • Washington D.C. had the highest chlamydia number of cases in the nation in 2023
  • Southern states dominate the rankings, occupying six of the top ten positions
  • Alaska is the only non-Southern state in the top five
  • Geographic disparities reflect differences in STI testing access, public health resources, and prevention programs

Washington D.C. leads with 1,228 cases per 100,000 population, almost 50% higher than any state. This high rate reflects urban density, transient populations, and healthcare access patterns that drive both testing and detection.

Louisiana ranks second at 792 cases, followed by American Samoa (771) and Mississippi (701). The South dominates the rankings, with six of the top ten spots occupied by Southern states including Alabama, Georgia, South Carolina, and North Carolina.

Alaska stands out as the only non-Southern state in the top five, driven by rural healthcare challenges, limited STI prevention resources in remote communities, and higher rates among Alaska Native populations.

These geographic disparities highlight regional differences in healthcare access, testing availability, public health funding, and sexually transmitted infection prevention programs across the country.

Data Source: Kaiser Family Foundation (KFF) (2023).


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